Twenty-three players from Big 12 schools are potentially slated to be on 2021 Major League Baseball rosters for Opening Day on Thursday. Official rosters for clubs will be formally announced leading up to game day.  
 
All nine Big 12 squads have one player on a major league roster. In total, the Conference is represented on 20 MLB rosters. TCU and Texas pace the way with five players each, followed by four from Oklahoma, three from Oklahoma State and two from West Virginia. Baylor, Kansas, K-State and Texas Tech each have one athlete on an MLB team.
 
Baylor’s Max Muncy returns to the Los Angeles Dodgers after winning the 2020 World Series. West Virginia pitcher John Means will get the nod as the Opening Day starter for the Baltimore Orioles.
 
All 30 MLB teams open the season on Thursday, April 1.
 
Players from Big 12 Schools on MLB Rosters (as of 3/31, 10 a.m. CT)
Note that rosters are subject to change and this list will be updated if there are changes
 
Baylor (1)
Max Muncy, 1B, Los Angeles Dodgers
 
Kansas (1)
Wes Benjamin, P, Texas Rangers
 
K-State (1)
Evan Marshall, P, Chicago White Sox
 
Oklahoma (4)
Chase Anderson, P, Philadelphia Phillies
Jon Gray, P, Colorado Rockies
Garrett Richards, P, Boston Red Sox
Burch Smith, P, Oakland Athletics
 
Oklahoma State (3)
Thomas Hatch, P, Toronto Blue Jays
Andrew Heaney, P, Los Angeles Angels
Jordy Mercer, SS, Washington Nationals
 
TCU (5)
Tyler Alexander, P, Detroit Tigers
Jake Arrieta, P, Chicago Cubs
Matt Carpenter, 3B, St. Louis
Stefan Crichton, P, Arizona Diamondbacks
Alex Young, P, Arizona Diamondbacks
 
Texas (5)
Brandon Belt, 1B, San Francisco Giants
John Curtiss, P, Miami Marlins
Corey Knebel, P, Los Angeles Dodgers
Mark Payton, LF, Cincinnati Reds
Brandon Workman, P, Chicago Cubs

Texas Tech (1)
Josh Tomlin, P, Atlanta Braves
 
West Virginia (2)
Ryan McBroom, 1B, Kansas City Royals
John Means, P, Baltimore Orioles