NORMAN, Okla. (AP) - Ryan Broyles broke the school record with 208 yards receiving as part of the biggest passing day in Oklahoma history, and the 11th-ranked Sooners bounced back from their first loss of the season to beat Colorado 43-10 on Saturday night.

Landry Jones threw for a career-high 453 yards and four touchdowns, including three to Broyles. Jones' total was the second-best in school history, behind only Sam Bradford's 468 against Kansas in his 2008 Heisman Trophy season. When combined with backup Drew Allen's 35 yards, the Sooners (7-1, 3-1 Big 12) broke the school record for passing set on Bradford's biggest day.

Colorado (3-5, 0-4) kept it close for a quarter before losing its 15th straight road game and its 11th conference game in a row, putting coach Dan Hawkins' already tenuous job status on even shakier ground.

After the Sooners managed only field goals on their first two trips inside the 20, Broyles started getting loose for big plays to lead the way to Oklahoma's 35th straight home victory - the longest current run in the nation.

He got wide open with the help of a Jones pump fake to catch a 16-yard touchdown pass, then beat Jonathan Hawkins for an 81-yard score to make it 20-3 in the second quarter. Broyles got a step behind Hawkins to make an over-the-shoulder catch and then raced the final 50 yards to finish the longest catch of his career. It was Jones' longest completion, too.

To start the second half, Broyles - who came in leading the nation with 9.9 catches per game - zoomed past Roy Polk on a post pattern for a 64-yard TD. Polk caught up just before the goal line, but Broyles was able to reach the ball into the end zone as he was turned on top of his head.

Cody Hawkins, taking the place of injured starting quarterback Tyler Hansen, threw a 49-yard touchdown pass to Scotty McKnight in the third quarter but came nowhere near duplicating the biggest win of his Colorado career that came in a 2007 upset against No. 3 Oklahoma.

Facing a sizable deficit, Cody Hawkins unleashed one pass after another and ended up trying enough that he matched the Buffaloes' career record for attempts set by Joel Klatt (1,095). He finished 17-for-44 for 187 yards.

DeMarco Murray had a career-high 10 catches for 73 yards, and tight end Trent Ratterree had three receptions for a career-best 89 yards for Oklahoma.

Javon Harris blocked a punt out of the side of the end zone for a safety, and James Hanna also caught a 7-yard TD pass for the Sooners.